Analysis and prevention of adverse transfusion reactions from 2012 to 2014

Objective To analyze and explore the causes of adverse reactions from blood transfusion by component transfusion and the measures to reduce adverse blood transfusion reactions in order to ensure the safety transfusion. Methods Clinical data and blood transfusion reports were analyzed in 57 171 patients from January 2012 to December 2014 in Affiliated Hospital of Zunyi Medical College Hospital. Adverse reactions from blood transfusion were counted to reflect the characteristics of adverse reactions of blood transfusion. Results 176 patients presented adverse reactions from blood transfusion which were mainly non-hemolytic febrile transfusion reactions and anaphylaxis without other adverse reactions and side effects of blood transfusion. The incidence of adverse reactions was 0. 31%,among which anaphylaxis,non-hemolytic febrile transfusion reactions and other reactions accounted for 0. 21%,0. 09% and 0. 01%,respectively. From component transfusion,platelets collected manually caused the highest rate of adverse effects,at 1. 05%,of which non-hemolytic febrile transfusion reactions and anaphylaxis accounted for 0. 26% and 0. 69%,followed by aphaeresis platelets,which accounted for 0. 56%.Fresh frozen plasma and suspended red blood cells made up 0. 29% and 0. 20% of adverse effects,and cryo accounted for the lowest,at 0. 11%. No adverse reactions were found due to transfusion of washed red blood cells. The rate of blood component transfusion was 99. 98% in our hospital,and whole blood transfusion occurred relatively less frequently,in which adverse reactions from blood transfusion were not recorded. Conclusion The main cause of adverse reactions from blood transfusion is anaphylaxis. Clinical medical workers should strictly follow transfusion indications and choose appropriate blood components and blood products. Knowledge of adverse reactions of blood transfusion should be obtained by relevant medical personnels. Measures to deal with adverse reactions of blood transfusion should be made and blood transfusion operationprocedures should be performed with caution to guarantee and improve the safety and effectiveness of transfusion.