Monitoring of bacterial drug resistance in our hospital in 2010

Objective:To investigate the distribution and antibiotic resistance characteristics of clinical bacterial isolates from our hospital in 2010 to guide clinical rational drug use.Methods:The disk diffusion method was adopted for performing the drug susceptibility test and ESBLs for detecting Enterobacteriaceae with Whonet5.3 software for data analysis.Results:1044 strains of bacteria were isolated from our hospital in year 2010,including 718 strains(68.8%) of Gram-negative bacteria and 326 strains(31.2%) of Gram-positive cocci.Escherichia coli and Staphylococcus aureus occupied the first place for Gram-negative bacilli and gram-positive cocci respectively.The detection rates of ESBLs in Escherichia coli and Klebsiella pneumoniae were 18.9% and 10.6% respectively.The detection rates of MRSA and MRCNS in Staphylococcus were 34.5% and 43.2% respectively.Conclusion:Bacteria isolated from the patients in our hospital have very serious drug resistance.Monitoring should be strengthened to guide rational use of antimicrobial drugs.