Antimicrobial Resistance of Pathogens in Nosocomial Respiratory Tract

OBJECTIVE To study the distribution and the drug resistance situation of bacteria isolated from inpatients and then to guide the experienced application of antibacterial agents. METHODS Agar diffusion method was used to determine the susceptibility to 12 kinds antibacterial agents of bacteria isolated from the hospital acquired pneumonia(HAP) patients′ sputum samples. RESULTS A total of 269 pathogenic strains were tested, including 182 strains of Gram negative bacilli and 87 strains of Gram positive cocci. Among Gram negative bacilli, the first 5 strains were Acinetobacter baumannii , Escherichia coli, Pseudomonas aeruginosa , Ctenotrophomonas maltophilia and Klebsiella pneumoniae. However, The most Gram positive cocci were Staphylococcus aureus . The microbial sensitivity test displayed the Gram negative bacilli were the most sensitive to imipenem and the Gram positive cocci were the most sensitive to vancomycin. CONCLUSIONS The multidrug resistance of bacteria isolated from inpatients is the difficulty to antibacterial treatment, then inspecting the distributing and the drug resistance changes of bacteria is important.