Treatment of lumbar intervertebral disc herniation with percutaneous lumbar discectomy and different collagenase injections

Objective: To compare and evaluate effects and adverse reaction of three different methods in the treatment of lumbar intervertebral disc herniation.Methods:Fifty-nine patients of lumbar intervertebral disc herniation,involving 36 cases of male and 23 cases of female with age from 19 to 69 (averagely 38.18±10.24) years,were divided randomly into three groups:Group A in which patients were treated with percutaneous lumbar discectomy and intervertebral disc injection (15 cases);group B,treated with percntaneous lumbar discectomy and epidural injection (26 cases);group C,treated by percntaneous lumbar discectomy,intervertebral disc and epidural injection (18 cases).Results:All the patients were followed up for more than 4 months.There were no significant difference in near-term and long-term clinical effects among the three different treatments.The total rates of excellent and good clinical effects were the same,i.e.72.88%,in the near-term and the long-term evaluations.The total effective rate was 96.61% in the near-term evaluation,and 86.44% in the long-term evaluation.Conclusion:The three different methods are effective for lumbar disc herniation,of which adverse reaction is few.