Distribution and drug resistance of pathogenic bacterial isolated from different kinds of wounds in burn wards

OBJECTIVE To analyze the distribution and drug resistance of pathogenic bacteria isolated from different kinds of wound in burn wards and provide the basis for clinical rational use of antimicrobial agents.METHODS Pathogenic bacteria were isolated from different kinds of wound in burn wards from Jan 2006 to Jun 2012.K-B slip diffusion method was taken to carry out the drug susceptibility testing.Rate of drug resistance of pathogenic bacteria was analyzed.RESULTS Totally 205 strains were isolated,with the detection rate of 71.18%,among which 91 strains were gram-positive bacteria,accounting for 44.39%,113 strains were gram-negative bacteria,accounting for 55.12%and 1 strain was fungus,accounting for 0.49%.In the common bacteria,Staphylococcus aureus were more common in burn refractory wound,while Pseudomonas aeruginosa and Acinetobacter baumannii were more common in non-burn refractory wound.Thedrug resistance rates of the gram-positive bacteria to penicillin,erythromycin,oxacillin,and clindamycin were more than 70.00%,while the drug resistance rates of the gram-negative bacteria to cefazolin,cefotaxime,amoxicillin,and clavulanic acid were more than 60.00%.The pathogens isolated from the three types of wound secretion differed in the drug resistance rate.CONCLUSION There are different distribution and drug resistance of pathogenic bacterial isolated from different kinds of wounds.We need to take different antimicrobial therapy measures for different kinds of wound in clinical treatment.