Distribution of Pathogenic Bacteria from Burn Wounds and Drug Resistance Analysis of 531 Cases
Hongli Zhao
Abstract
Hongli Zhao
Abstract
Objective:To analyze distribution of pathogenic bacteria from burn wounds and drug resistance,and to provide the basis for clinical prevention and treatment of infection.Methods:We collected 531 patients hospitalized for burn wounds during Jan.2005 and Dec.2008 and isolated and identified bacteria by conventional method from the injured area.Antibiotics spectrum was determined.Results:562 strains was isolated from the burn injured area(31 patients had two kinds of bacteria).And among them there were 258(45.91%) strains of gram-positive bacteria,the isolating rate of Staphylococcus aureus was the highest.There were 293(52.14%) strains of gram-negative bacteria,the isolating rate of Pseudomonas aeruginosa rate was the highest.There were 11(1.96%)real strains.The results of susceptibility test indicated that gram-positive bacteria were resistant to Penicillin,Rifampicin,Clindamycin and Ampicillin,while gram-negative bacteria were resistant to Penicillin,Cephazolin,Ampicillin and Fosfomycin.Conclusion:The bacteria from burn wounds has high resistance to various antibiotics,and drug resistance should be monitored in order to provide clinical basis for reasonable use of antibiotics.
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Objective:To analyze distribution of pathogenic bacteria from burn wounds and drug resistance,and to provide the basis for clinical prevention and treatment of infection.Methods:We collected 531 patients hospitalized for burn wounds during Jan.2005 and Dec.2008 and isolated and identified bacteria by conventional method from the injured area.Antibiotics spectrum was determined.Results:562 strains was isolated from the burn injured area(31 patients had two kinds of bacteria).And among them there were 258(45.91%) strains of gram-positive bacteria,the isolating rate of Staphylococcus aureus was the highest.There were 293(52.14%) strains of gram-negative bacteria,the isolating rate of Pseudomonas aeruginosa rate was the highest.There were 11(1.96%)real strains.The results of susceptibility test indicated that gram-positive bacteria were resistant to Penicillin,Rifampicin,Clindamycin and Ampicillin,while gram-negative bacteria were resistant to Penicillin,Cephazolin,Ampicillin and Fosfomycin.Conclusion:The bacteria from burn wounds has high resistance to various antibiotics,and drug resistance should be monitored in order to provide clinical basis for reasonable use of antibiotics.
Key concepts: Ampicillin, Microbiology, Penicillin, Bacteria, Antibiotics, Medicine, Pathogenic bacteria, Clindamycin