The Significance of ThinPrep liquid based cytology test(TCT) in Diagnosis of tumor in urinary system

Objective To make comparison of the detection rates of tumor in urine system between ThinPrep liquid based cytology test(TCT) and conventional Pap smears.Methods 120 urine specimens of patients from out-patient clinics and urology in-patient department of the first hospital of Jilin University were randomly selected from April to December in 2010,Adopt ThinPrep 2000 liquid-based Pap smear sampling devices and conventional cytology method to prepare smears respectively.After Pap staining,compare the detection rate of tumor between the two methods under a microscope.Five-category classification diagnosis criteria were used in diagnosis,test results compared with pathology diagnose.Results There were 41 postitive result cases of 120 specimens.included 31 postitive result cases of TCT,of which the sensitivity was 75.6%,and 17 postitive result cases of conventional cytology method,of which the sensitivity was 41.5%.The sensitivity of TCT improved 34.1%.Utilize chi-square test,P values 0.05,there was statistical significance and the diagnosis was consistent with pathological findings.Conclusion Compared with conventional cytology,the TCT provided more effective detection rate and correspondence rate.Accordingly,TCT can improve the diagnostic sensitivity of tumor in urinary system.