Clinical Analysis of Primary Malignant Gastric Lymphoma (A Report of 22 cases)

Objective To investigate the clinical and endoscopic features of patients with primary malignant gastric lymphoma. Methods Clinical, gastroscopic features and pathological results of 22 patients were analyzed and summarized. Results There was no specific clinical features. Epigastric pain was the most frequent symptom (22/22), upper alimentary tract bleeding (16/22), acid regurgitation and belching (6/33) were also noticed. Gastroscopic features: tumors involving two parts of stomach were found in 10 patients (10/22), gastic body (6/22) and gastric antrum (3/22), respectively. Tumor size was larger than 2cm in 17 pativents (17/ 22); The most frequent type was ulcer-type tumor, and the second one was diffused infiltrating-type. The diagnosis rate of gastroscopic biopsy and immunohistochemistry was 63.63% (14/22); The detection rate of H.pylori was 86.36%. Conclusions Primary malignant gastric lymphoma has no specific clinical features. However, it has various appearances under gastroscopy. In most patients, the tumor involves more than 2 parts of the stomach. Gastroscopic biopsy and immunohistochemistry is an important method to diagnose this disease. H.pylori infection is related to the oncogenesis of Primary Malignant Gastric Lymphoma.