Clinical and endoscopic features of primary gastric lymphoma

[Objective] To explore the clinical and endoscopic features of primary gastric lymphoma. [Methods] The clinical, endoscopic and pathologic data of 24 patients with primary gastric lymphoma identified by histology were analgzed. [Results] The symptoms were not characteristic. Upper abdominal pain was most common. Misdiagnosis rate was 91.7%.The tumor originated from antrum and corpus in 10 cases, corpus 9, antrum 4, fundus 1. The tumor appeared ulcerative in 18 cases, in filtrative 4, nodular 2. The detection rate of endoscopic biopsy was very low (41.7%) Immunohistochemistry showed B-cell lymphoma in mostly case. Helicobacter pylori (H.pylori) infection was found in 20 case (83.3%). [Conclusions] Noclinical symptoms and signs have been found specific for the diagnosis of primary gastric lymphoma. The endoscopic features are variegated and the lesion is more extensive. Multi-point biopsy and deep biopsy can improve confirmed diagnosis rate. H.pylori infection may play a role in the pathogenesis of primary gastric lymphoma.