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Study on Acute Toxicity and Genetic Toxicity of Some Health Food Containing Pueraria Flavonoid

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Abstract

[Objective]To study the acute toxicity and genetic toxicity of some health food containing pueraria flavonoid and assess the security of these health food.[Methods]To detect the toxicity of health food by acute toxicity test of mice,Ames test,micronucleus test of bone marrow PCE cell in mice and sperm shape abnormality test of mice.[Results]Pueraria flavonoid had no toxicity to mice according to the acute toxicity.The results of genetic toxicity test were all negative,including Ames test,micronucleus test and sperm shape abnormality test.[Conclusion]Pueraria flavonoid was a substance with no toxicity and showed no genetic toxicity in these test.

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What this paper is about

[Objective]To study the acute toxicity and genetic toxicity of some health food containing pueraria flavonoid and assess the security of these health food.[Methods]To detect the toxicity of health food by acute toxicity test of mice,Ames test,micronucleus test of bone marrow PCE cell in mice and sperm shape abnormality test of mice.[Results]Pueraria flavonoid had no toxicity to mice according to the acute toxicity.The results of genetic toxicity test were all negative,including Ames test,micronucleus test and sperm shape abnormality test.[Conclusion]Pueraria flavonoid was a substance with no toxicity and showed no genetic toxicity in these test.

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Available abstract

[Objective]To study the acute toxicity and genetic toxicity of some health food containing pueraria flavonoid and assess the security of these health food.[Methods]To detect the toxicity of health food by acute toxicity test of mice,Ames test,micronucleus test of bone marrow PCE cell in mice and sperm shape abnormality test of mice.[Results]Pueraria flavonoid had no toxicity to mice according to the acute toxicity.The results of genetic toxicity test were all negative,including Ames test,micronucleus test and sperm shape abnormality test.[Conclusion]Pueraria flavonoid was a substance with no toxicity and showed no genetic toxicity in these test.

Key concepts: Toxicity, Ames test, Acute toxicity, Micronucleus test, Micronucleus, Pueraria, Flavonoid, Pharmacology

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