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2014•China Medical HeraldRequires access

Experimental study of acute toxicity and genetic toxicity test of pueraria flower

Guan Zetin

Open publisher page 1 citations

Abstract

Objective To study the acute toxicity and genetic toxicity test of pueraria flower. Methods Acute toxicity and genetic toxicity(including Ames test, micronucleus test of bone marrow cells in mice and sperm abnormality test in mice) were tested to observe the toxicological reaction of pueraria flower. Results The MTD of pueraria flower was higher than 30 g/kg BW, belonged to the non-toxic level. Ames test, micronucleus test of bone marrow cells in mice and sperm abnormality test in mice were all negative. Conclusion Pueraria flower is non-toxic.

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What this paper is about

Objective To study the acute toxicity and genetic toxicity test of pueraria flower. Methods Acute toxicity and genetic toxicity(including Ames test, micronucleus test of bone marrow cells in mice and sperm abnormality test in mice) were tested to observe the toxicological reaction of pueraria flower. Results The MTD of pueraria flower was higher than 30 g/kg BW, belonged to the non-toxic level. Ames test, micronucleus test of bone marrow cells in mice and sperm abnormality test in mice were all negative. Conclusion Pueraria flower is non-toxic.

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Available abstract

Objective To study the acute toxicity and genetic toxicity test of pueraria flower. Methods Acute toxicity and genetic toxicity(including Ames test, micronucleus test of bone marrow cells in mice and sperm abnormality test in mice) were tested to observe the toxicological reaction of pueraria flower. Results The MTD of pueraria flower was higher than 30 g/kg BW, belonged to the non-toxic level. Ames test, micronucleus test of bone marrow cells in mice and sperm abnormality test in mice were all negative. Conclusion Pueraria flower is non-toxic.

Key concepts: Toxicity, Micronucleus test, Acute toxicity, Medicine, Pueraria, Ames test, Sperm, Micronucleus

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