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2005•Journal of Beijing Union UniversityRequires access

The Assessment of the Genetic Toxicity of Tea Oil

Jia Yuqiao

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Abstract

Objective:To evaluate the genetic toxicity of tea oil.Methods:Acute oral toxicity test in mice, Ames test, micronucleus test of bone marrow PCE cell and sperm abnormality test in mice were used. Results:LD_(50) of tea oil is more than 20 mL/kgBW by the acute toxicity. The results of genetic toxicity tests are all negative,including Ames test, micronucleus test and sperm adnormality test. Conclusion:Tea oil was considered a substance with no toxicity and mutagenic activity.

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What this paper is about

Objective:To evaluate the genetic toxicity of tea oil.Methods:Acute oral toxicity test in mice, Ames test, micronucleus test of bone marrow PCE cell and sperm abnormality test in mice were used. Results:LD_(50) of tea oil is more than 20 mL/kgBW by the acute toxicity. The results of genetic toxicity tests are all negative,including Ames test, micronucleus test and sperm adnormality test. Conclusion:Tea oil was considered a substance with no toxicity and mutagenic activity.

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Available abstract

Objective:To evaluate the genetic toxicity of tea oil.Methods:Acute oral toxicity test in mice, Ames test, micronucleus test of bone marrow PCE cell and sperm abnormality test in mice were used. Results:LD_(50) of tea oil is more than 20 mL/kgBW by the acute toxicity. The results of genetic toxicity tests are all negative,including Ames test, micronucleus test and sperm adnormality test. Conclusion:Tea oil was considered a substance with no toxicity and mutagenic activity.

Key concepts: Micronucleus test, Ames test, Toxicity, Acute toxicity, Sperm, Micronucleus, Toxicology, Pharmacology

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