A retrospective study of the elderly patients with paroxysmal supraventricular tachycardia treated with drug

Objective:To compare the efficacy and safety of antiarrhythmic agents the Class Ic propafenone and the ClassⅣ verapamil on the elderly patients with paroxysmal supraventricular tachycardia(PSVT).Method:A randomized controlled trial with a total of 68cases in emergency department from 2008to 2012were divided into propafenone and verapamil group randomly.34elderly patients with PSVT were given intravenous propafenone at a rate of 10mg per minute to a maximum dose of 140mg.34elderly patients with PSVT were given intravenous verapamil at a rate of 1mg per minute up to a maximum dose of 10mg.These infusions would be stopped at time of conversion of the elderly patients with PSVT.Heart rate and blood pressure was continuously monitored during drug infusion and for up to 2hpost-conversion.Result:68elderly patients with PSVT were analyzed.Of these,34 were given propafenone and 34were administered verapamil.The total effective rate of propafenone and verapamil on the elderly patients with PSVT were 91.2%and 88.2%,respectively.Conclusion:When we select antiarrhythmic agents,each patient must be individualized and tailored to each patient's physiology,disease processes,and medication regimen.