Comparative Analysis between Laparoscopic Surgery and Laparotomy for Gastric Cancer on Coagulation

Objective To investigate the difference between laparoscopic surgery and laparotomy for gastric cancer on blood coagulation. Methods Blood coagulation was determined by detecting the values of the PT, APTT, FIB and INR, and enzyme linked immunosorbent assay (ELISA) was used to detect the value of DD before operation, 24th hour after operation in 35 patients under laparoscopic surgery or laparotomy for gastric cancer respectively. Results Compared with pre-operation, no change in the values of APTT and INR at the end of operation and 24th hour post-operation could be observed in both two groups. The values of FIB and DD markedly increased at the end of operation and 24th hour post-operation in both two groups, and there were significant difference between two groups (P0.05). The values of PT decreased at 24th hour post-operation sharply in two groups, but there were no significant difference. Conclusion The effect of laparoscopic surgery appeared to make coagulation strata vary more significantly than laparotomy operation, which would increase the incidence of deep vein thrombosis. So it is requisite to perform the treatment of anti-coagulation on the patients with laparoscopic surgery.