Optimization of Fermentation Medium forε-polylysine Producion

To increase the production ofe-polylysine from Streptomyces C1,response surface method was applied to optimize the fermentation medium on the basis of orthogonal test.The results showed that the optimum fermentation medium was glucose of 23.0g/L,beef extract of 4g/L, peptone of 3g/L,C6H14N2O7of 1.84g/L,pH value of 4.0.Under the above condition,the yield ofe-polylysine reached 0.86g/L,which was closed to the level(0.80g/L)predicted by model.