The clinical observation on the Enalapril combined with Amlodipine Besylate in treatment of essential hypertension

Objective: To study the effects of Enalapril combined with Amlodipine Besylate in treatment of essential hypertension.Methods: 98 patients with essential hypertension from January 2008 to October 2010 were selected as research object,and all the patients were randomly divided into control group(Amlodipine Besylate group)49 cases and observation group(Enalapril combined with Amlodipine Besylate group)49 cases,then the total effective rate,incidences of adverse reactions and the blood pressure,situation of cardiac hypertrophy before and after the treatment were studied and compared.Results: The total effective rate of observation group was higher than that of control group,the improvement of cardiac hypertrophy was better than that control group,there were significant differences(all P0.05),but the incidences of adverse reactions of the two groups were compared,there were no significant differences(P0.05).Conclusion: The effect of Enalapril combined with Amlodipine Besylate in essential hypertension is better,and it deserves further clinical applications.