Effect of Weiyanyin on the gastric mucosa pathomorphology of Experiment Gastric ulcer in rats

Objective To observe the effect of Weiyanyin on the gastric mucosa pathomorphology of experimental gastric ulcer in rats. Methods The model of experiment gastric ulcer was made by the corrosion of glacial acetic acid. Compared with Omeprazole,the effect of Weiyanyin on the gastric mucosa pathomorphology of experimental gastric ulcer in rats was observed. Results Compared with model group,the ulcer area of drug group was significant reduced( P 0. 01 or P 0. 05); Compared with Omeprazole group,the ulcer area of Weiyanyin high-dose group was significant reduced( P 0. 05); The ulcer inhibition rate of Weiyanyin high-dose group was higher than Weiyanyin low-dose group and Omeprazole group. Conclusion Weiyanyin could significantly improve the pathomorphology of rats gastric ulcer model,promote ulcer healing,increase the rate of ulcer healing,and have certain therapeutic effect on gastric ulcer.