The value of C-12 multiple tumor markers protein chip diagnosis system in the differential diagnosis of benign and malignant adnexal masses

Objective To explore the reliability and validity of C-12 multiple tumor markers protein chip detection system for the differential diagnosis of benign and malignant adnexal masses.Methods The levels of 12 tumor markers(AFP,CA125,CA199,CEA,CA153,CA242,Ferritin,β-HCG,NSE,HGH,f-PSA and PSA)were detected by protein chip technology for 100 physical examiners and 130 ovarian tumor,including 60 malignant patients,70 benign patients.Results The levels of CA125,CA199,CA242 and CEA of malignant group were remarkably higher than those of the benign group and normal group(P﹤0.05).Other tumor makers had no significant difference(P﹥0.05).The allied detection of CA125,CA199,CA242 and CEA had raised diagnostic sensitivity and accuracy.Conclusion Multiple tumor markers protein chip diagnosis system is helpful to the differential diagnosis of benign and malignant adnexal masses,it can increase the diagnostic sensitivity and accuracy of malignant ovarian tumor guide clinical treatment.