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2005•Carcinogenesis,Teratogenesis and MutagenesisRequires access

The Influence of Intraoperative Radiation Therapy on Immunity of Patients with Cervical Cancer in II_b Stage

Liwen Liu

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Abstract

BACKGROUNDAIM: To explore peripheral blood T-lymphocyte subsets and interleukin-2(IL-2)level in patients with cervical cancer inⅡ b stage before and after intraoperation radiation therapy(IROT). MATERIAL AND METHODS: Before and after radiotherapy,the T-lymphocyte subsets and IL-2were measured in61patients with cervical cancer inⅡ b stage,including28patients with IROT and31ones with simple radiotherapy(SR),and contrasting to20normal controls by using flow cytometry and radio immune assay. RESULTS: After radiotherapy,the radio CD 4 ,CD 4 /CD 8 and IL-2with IROT were significantly higher than those with SR. CONCLUSION: The influence of IROT on immunity of patients with cervical cancer inⅡ b stage was lighter than that of SR.So,IROT contribute to recovery after radiotherapy.

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What this paper is about

BACKGROUNDAIM: To explore peripheral blood T-lymphocyte subsets and interleukin-2(IL-2)level in patients with cervical cancer inⅡ b stage before and after intraoperation radiation therapy(IROT). MATERIAL AND METHODS: Before and after radiotherapy,the T-lymphocyte subsets and IL-2were measured in61patients with cervical cancer inⅡ b stage,including28patients with IROT and31ones with simple radiotherapy(SR),and contrasting to20normal controls by using flow cytometry and radio immune assay. RESULTS: After radiotherapy,the radio CD 4 ,CD 4 /CD 8 and IL-2with IROT were significantly higher than those with SR. CONCLUSION: The influence of IROT on immunity of patients with cervical cancer inⅡ b stage was lighter than that of SR.So,IROT contribute to recovery after radiotherapy.

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Available abstract

BACKGROUNDAIM: To explore peripheral blood T-lymphocyte subsets and interleukin-2(IL-2)level in patients with cervical cancer inⅡ b stage before and after intraoperation radiation therapy(IROT). MATERIAL AND METHODS: Before and after radiotherapy,the T-lymphocyte subsets and IL-2were measured in61patients with cervical cancer inⅡ b stage,including28patients with IROT and31ones with simple radiotherapy(SR),and contrasting to20normal controls by using flow cytometry and radio immune assay. RESULTS: After radiotherapy,the radio CD 4 ,CD 4 /CD 8 and IL-2with IROT were significantly higher than those with SR. CONCLUSION: The influence of IROT on immunity of patients with cervical cancer inⅡ b stage was lighter than that of SR.So,IROT contribute to recovery after radiotherapy.

Key concepts: Radiation therapy, Medicine, Stage (stratigraphy), Immunity, Cervical cancer, Flow cytometry, Immune system, Oncology

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The Influence of Intraoperative Radiation Therapy on Immunity of Patients with Cervical Cancer in II_b Stage — Research Paper | ScholarLens