2002Zhongguo mianyixue zazhiRequires access

The changes of immunity and clinical significance in patients with cervical cancer before and after radiotherapy

Cheng He

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Abstract

Objective:To investigate the influence of radiotherapy on immunity of patients with cervical cancer Methods:22 cancer patients and 20 patients with gynecological benign tumor were immunothenotype by flow cytometry Results:There was no obvious difference in immunity between cancer patients and control group After radiopherapy, ratio CD3 +/CD4 + decreased and the number of CD8 + and NK cells increased in cancer patients Conclusion:No immunodepression appeared in patients with cervical cancer before therapy Radiotherapy decreased immunity, which indicates adjuvant immunotherapy should be given during radiotherapy

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Objective:To investigate the influence of radiotherapy on immunity of patients with cervical cancer Methods:22 cancer patients and 20 patients with gynecological benign tumor were immunothenotype by flow cytometry Results:There was no obvious difference in immunity between cancer patients and control group After radiopherapy, ratio CD3 +/CD4 + decreased and the number of CD8 + and NK cells increased in cancer patients Conclusion:No immunodepression appeared in patients with cervical cancer before therapy Radiotherapy decreased immunity, which indicates adjuvant immunotherapy should be given during radiotherapy

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Available abstract

Objective:To investigate the influence of radiotherapy on immunity of patients with cervical cancer Methods:22 cancer patients and 20 patients with gynecological benign tumor were immunothenotype by flow cytometry Results:There was no obvious difference in immunity between cancer patients and control group After radiopherapy, ratio CD3 +/CD4 + decreased and the number of CD8 + and NK cells increased in cancer patients Conclusion:No immunodepression appeared in patients with cervical cancer before therapy Radiotherapy decreased immunity, which indicates adjuvant immunotherapy should be given during radiotherapy

Key concepts: Medicine, Radiation therapy, Cervical cancer, Immunity, Adjuvant, Cancer, CD8, Flow cytometry

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