Analysis of the lipid metabolism,glu,liver and kidney function relevant indicators changes in patients with coronary atherosclerotic heart disease

Objective To analysis the changes and correlation of lipid metabolism,fasting blood glucose(Glu) and liver and kidney function related indicators in patients with coronary atherosclerotic heart disease(CHD). Methods Selecte 1 586 CHD patients as the observation group,and 1 512 healthy people as the control group. Using automatic biochemical analyzer to analyze the total cholesterol(TC),triglyceride( TG),high density lipoprotein cholesterol( HDL-C),low density lipoprotein cholesterol(LDL-C),apolipoprotein A1(ApoA1),apolipoprotein B(ApoB),lipoprotein a(Lipa),Glu levels total bilirubin(TBIL),direct bilirubin(DBIL),indirect bilirubin(IBIL),alanine aminotransferase(ALT),aspartate aminotransferase(AST),blood urea nitrogen(BUN),creatinine(Cr). Results Compared with the control group,the TC,TG,LDL-C,ApoB,Lipa levels of the observation group were significantly higher,and the HDL-C,HDL-C /LDL-C,HDL-C /TC,ApoA1,ApoA1 /ApoB,TBIL,DBIL,IBIL levels were significantly lower,the difference is statistically significant. The HDL-C,ApoA1 levels of CHD patients were positively correlated with TBIL,and the TC,TG,LDL-C,ApoB,Lipa were negatively correlated with TBIL,and also related to thelesions of coronary atherosclerosis. Conclusion Significantly lower levels of lipid metabolism,bilirubin were closely related to CHD,which are risk factors for CHD. Early intervention may prevent cardiovascular events occurring and developing.