Detection of serum non-high-density lipoprotein cholesterol levels in patients with nonalcoholic fatty liver

Objective To understand the clinical significance of serum non-high-density lipoprotein cholesterol(non-DHL-C) levels in the patients with nonalcoholic fatty liver.Methods The nonalcoholic fatty liver and the health persons(contrast group) physical examination were compared by image analysis and blood serum biochemical indicators about liver function,blood glucose(Glu) and blood fat.Results The detection rate of fatty liver was 9.15%.The rate of male patients was 12.50%,which was higher than that of female patients,5.99%(P0.05).There were significant differences in the levels of alanine aminotransferase(ALT),indirect bilirubin(IBiL),triglyeride(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),apolipoprotein a(apoA1),non-HDL-C,apoB100/apoA1,LDL-C/HDL-C,apoB100/HDL-C and TC/HDL-C between male patients and contrast group(P0.05 or P0.01),also in the mevels of aspartate aminotransferase(AST),total bilirubin(TBiL),direct bilirubin(DBiL),IBiL,Glu,TC,TG,LDL-C,apoA1,non-HDL-C,apoB100/apoA1,LDL-C/HDL-C,apoB100/HDL-C and TC/HDL-C between female patients and contrast group(P0.05 or P0.01).Non-HDL-C was obviously associated with TC,LDL-C,TG,HDL-C,apoA1,apoB100,apoB100/apoA1 and TC/HDL-C(r=0.411-0.989,P0.01).Conclusion The metabolism disorders exist in the patients with nonalcoholic fatty liver.Early detection of serum non-HDL-C levels may be helpful to know the metabolism condition of plasma lipids.