Clinical Research of Female Idiopathic Overactive Bladder(Kidney Qi Deficiency)Treated with Bushen Tonglin Decoction

Objective:To evaluate the efficacy and safety of bushen tonglin decoction in the treatment of female idiopathic overactive bladder(IOAB).Methods:96 female cases that met the inclusive criteria were optioned clinically and randomized into treatment group and control group,48 cases in each one.In treatment group,bushen tonglin decoction was administered orally,100 mL/time,twice per day.In control group,tolterodine tartrate tablet was prescribed for oral administration,2 mg/time,twice per day.The clinical efficacy was observed in two groups.Results:In treatment of 4 weeks,the total effective rate was 87.50% in treatment group and was 70.83% in control group.The total effective in treatment group was superior to that in control group(P0.05).The overall incidence of adverse event was 0 in treatment group and was 36.5% in control group,of which,the incidence of dry mouth was 23.3%.In treatment group,the improvements in urgent and painful urine with burning sensation were obvious as compared with control group,but the improvement in frequent urine was same as that in control group.Conclusion:Bushen tonglin decoction is safe and effective in treatment of female IOAB.