Curative observation of nifedipine sustained-release tablet combined with enalapril in the treatment of 48 patients with hypertension

Objective To observe the decompression effect,adverse reaction and metabolism effect of nifedipine sustained-release tablet combined with enalapril.Methods Ninety-six patients with hypertension were randomly divided into treatment group and control group,in which there's 48 patients respectively,the patients in treatment group were treated with nifedipine sustained-release tablet combined with enalapril,and only enalapril were given in control group,this course of treatment was 4 weeks,their blood presure were measured by the same doctor from beginning to end,and the blood sugar,blood-lipid,electrolyte,hepatic function and renal function before and after treatment were determined,and also did electrocardiogram.Results After treatment for four weeks,the effectiveness rate of treatment group and control group were 45.8 percent and 25.0 percent respectively,and the total effective rate were 95.8 percent and 68.7 percent respectively.There were significant difference between the two groups(P0.05 or P0.01),and no effects on glycometabolism,lipid metabolism,electrolyte,hepatic function,renal function and electrocardiogram of the two groups.Conclusion There is very good effects of nifedipine sustained-release tablet combined with enalapril on the decompression,with less side effect,it is well worth widely using in clinic.