Detection and antibiotics resistance for Shigella from diarrhea cases in Zhengzhou city (2005)

Objective To investigate the incidence, clinical symptom, serotype distribution and variance of antibiotics resistance of Shigellosis for the guidance of clinical medication. Methods According to the “Project for Surveillance of Shigellosis in China”, the detection, isolation and identification for Shigella spp were performed. K-B diffusion method was used to test drug susceptibility. Results 42 strains of Shigella were isolated from 185 diarrhea cases (22.7%), among them, 39 strains were S. flexneri, 92% (39/42), and 3 strains were S.sonnei, 7.1% (3/42). Among the 39 strains of S. flexneri, 24 strains were F4c (57.1%), 8 strains were F1a (19.0%), 5 strains were F2a (11.9%) and 2 strains were Fx variety (4.7%). F4c was the major prevalence serotype. Ten kinds of antibiotics susceptibility test showed that both S. flexneri and S.sonnei were resistant to nalidixic acid, SMZ-TMP and SMZ-TMP, the resistance rates of S. flexneri strains were 100%, 82.05% and 79.49% respectively, while S.sonnei strains were 100% drug resistant. Conclusion