Clinical significence of mifepristone and desogestrel-ethinylestradiol in the treatment of dysfunctional uterine bleeding perimenopausal period

Objective To assess the efficacy of mifepristone and desogestre-ethinylestradiol in the treatmen of dysfunctional uterine bleeding in perimenopausal period. Methods The results of mifepristone and desogestrel-ethinylestradiol treatment were analyzed in 110 patients with perimenopausal period dysfunctional uterine bleeding. Results There was no statistical difference in effective rate of mifepristone group and desogestrel-ethinylestradiol group(P0.05).Two groups both had few adverse reactions. Conclusion Mifepristone is as effective as desogestrel-ethinylestradiol in treatment of perimenopausal-period dysfunctional uterine bleeding,and the safety of long time mifepristone treatment should be considered.