Clinical Evaluation of three Methods in the Treatment of Keloid

Objective To evaluate the effect of three methods of treatment of keloids:excision combined with postoperative radiation,excision combined with intralesional injection of steroid and intralesional injection of steroid.Methods Patients with keloids were divided into groupA,B and C.In group A,keloids were removed by operation,followed by 90Sr-90Y irradiation of total doses of 900 cGy,100～200 cGy of which was applied every other day 5 times a couse and 2-3 courses would be required to be cured.In group B,patients were treated with intralesional injection of 40 mg triamcinolone during and after operation excision,which was repeated once 2 weeks,4-8 times in total.Patients of group C were treated with intralesional injection of single 40mg triamcinolone every 2 weeks,8-12 times in total.Results After respective treatment,all patients were followed up for 24 months.The overall efficacy was 0.83%,0.80%,and 0.53% in group A,B and C respectively.There was significant difference between group A and C(P0.05),as is between group B and C.Conclusion It was concluded that the effect of the combined therapy is more satisfactory than that of a single approach.