Clinical observation of the therapeutic efficacy of surgical excision combined with triamcinolone acetonide injection and 90Sr-90Y applicator brachytherapy for the treatment of keloids

Objective: To evaluate the the efficacy and safety of surgical excision combined with triamcinolone acetonide injection and 90 Sr- 90 Y applicator brachytherapy for the treatment of keloids. Methods: Sixty-one patients with keloids were divided into the treatment group（n=31） and the control group（n=30） randomly. All the patients were given surgical excision,and the patients received intradermal injection of triamcinolone acetonide immediately following the surgery. The treatment group was treated with 90 Sr- 90 Y applicator brachytherapy once every two days for 6 times within 3 days after the surgery. All the patients were followed up for 12 to 24 months for the assessment of clinical efficacy. Results: All the incisions healed by first intention. After following up for 12 to 24 months, the cure rates of the treatment group and the control group were70.96% and 43.33%, respectively, with a significant difference between the two groups（P 90 Sr- 90 Y applicator brachytherapy is effective and safe for the treatment of keloids.