2008•Liaoning Zhongyiyao Daxue xuebaoRequires access

Protective Effects of The Yuegan Capsule on Primary Cultured Rat Hepatocytes

Cai Ying-mao

Abstract

Objective:To investigate the effects of Yuegan capsule on CCl4-intoxicated primary cultured rat hepatocytes.Methods:Hepatocytes injury models were induced by CCl4 in rats in vitro,and treated with Yuegan capsule.Effect of SDH,ACPase,G-6-Pase activeties and amount of hepatic glycogen were observed.Results:The Yuegan capsule increased the activity of SDH,G-6-Pase and the amount of hepatic glycogen(P0.001),and restrain the activety of ACPase(P0.001).Conclusion:Yuegan capsule had protective effects on CCl4-induced injury of primary cultured rat hepatocytes.

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Key concepts: CCL4, Capsule, Medicine, Glycogen, Hepatocyte, In vitro, Endocrinology, Internal medicine