2006•Lishizhen Medicine and Materia Medica ResearchRequires access

The Antiaging Effects of Yuegan Capsule on Mice Cultured Hepatocytes in vitro

Cai Ying-lan

Abstract

ObjectiveTo observe the antiaging effects of Yuegan capsule.Methods Hepatocytes injury models were induced by D-galactose in rats in vitro,and treated with Yuegan capsule.Structure,cytochemistry of rat hepatocytes and effect of SOD,MDA activities were observed. Results Yuegan Capsule decreased the content of MDA and increased SOD activity.According to the observation of histochemistry and ultrastructure,it showed that SDH activity decreased,ACP activity increased,the mitochondrion swelled and became deformed,crest broke.Yuegan capsule alleviated denatured degree above.Conclusion The Yuegan Capsule has protective effects on D-galactose-induced injury of primary cultured rat hepatocytes.

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Key concepts: Capsule, Cytochemistry, In vitro, Ultrastructure, Hepatocyte, Chemistry, Mitochondrion, Galactose