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[Protective effect of ganfukang capsule on hepatocytes in rats with experimental hepatic fibrosis].

Ying Che, Tingting Xu, Jiang Miaona, Yujie Jia

Abstract

OBJECTIVE: To observe the protective effect of ganfukang capsule on hepatocytes of rats with experimental hepatic fibrosis rat. METHOD: SD rat model of liver fibrosis was induced by CCl4. The effect of ganfukang capsule on liver function, histological change and ultrastructural were examined. RESULTS: Liver function, histological change and ultrastructural were significantly improved. The degree of steatosis was significantly decreased. CONCLUSION: Ganfukang capsule might protect hepatocytes, mitochondria from the injury induced by CCl4 and improve liver function.

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Key concepts: Capsule, Steatosis, CCL4, Ultrastructure, Fibrosis, Liver function, Carbon tetrachloride, Pathology