2006•Lishizhen Medicine and Materia Medica ResearchRequires access

Protective Effects of Yuegan Capsule on CCl_4-induced Injury of Primary Cultured Rat Hepatocytes

Jin Mei-shan

Abstract

ObjectiveTo investigate the effects of Yuegan Capsule on CCl_4-intoxicated primary cultured rat hepatocytes.MethodsHepatocytes injury models were induced by CCl_4 in rats in vitro,and treated with Yuegan capsule.Structure of rat hepatocytes and effect of SDH、ACPase、G-6-Pase activeties and amount of hepatic glycogen were observed.ResultsThe Yuegan Capsule increased the activity of SDH,G-6-Pase and the amount of hepatic glycogen,and restrain the activity of ACPase,and could improve the changes of rat hepatocytes structure.ConclusionYuegan capsule has protective effects on CCl_4-induced injury of primary cultured rat hepatocytes.

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Key concepts: Capsule, Hepatocyte, Glycogen, In vitro, Chemistry, Primary (astronomy), Endocrinology, Pharmacology