Therapeutic effect of Calsurf on neonatal respiratory distress syndrome

Objective To explore the clinical therapeutic effect of Calsurf for neonatal respiratory distress syndrome(NRDS).Methods Fifty-two neonates with NRDS were divided into two groups.Twentysix received Calsurf and the other twenty-six didn't receive Calsurf.The breathing machine ventilating parameter,the duration of mechanical ventilation and the pH,PaO2,PaCO2 of neonates after treatment in the two groups were compared.Results In the therapeutic group,the breathing machine ventilating parameter and the duration of mechanical ventilation were lower significantly than those in the control group.The pH,PaO2,PaCO2 of neonates in the treatment group were improved significantly after treatment(P0.05).There were significant differences between the two groups(P0.05).There was no complications such as pneumonia,pneumorrhagia and intracranial hemorrhage.Conclusion The treatment with Calsurf for NRDS can signifiacantly improve the therapeutic effect.It is safe to use Calsurf for neonates.