Clinical research on relationship between Chlamydia trachomatis,Ureaplasma urealyticum infection and infertility and drug resistance analysis of Ureaplasma urealyticum

Objective:To analyze the relationship between Chlamydia trachomatis(CT),Ureaplasma urealyticum(UU) infection and infertility and drug resistance of UU.Methods:A total of 246 infertile women were selected as observation group,and 134 women with normal infertility were selected as control group;the positive rates of CT and UU in the two groups were observed,the prevalences of upper reproductive tract inflammation and tubal obstruction in patients with positive and negative CT infection and UU infection and drug resistance of UU infection in the two groups were analyzed and observed.Results:There were statistically significant differences in infection rates of CT and UU,and mixed infection rate of CT and UU between the two groups(P0.001);in observation group,there were statistically significant differences in the prevalences of upper reproductive tract inflammation and tubal obstruction between patients with positive CT infection and UU infection and patients with negative CT infection and UU infection(P0.001);the results of drug sensitive test showed that UU was sensitive to doxycycline and minocyline,drug resistances of ciprofloxacin and norfloxacin were serious.Conclusion:CT and UU infection of urogenital system are closely related to infertility;drug sensitive test can direct clinical drug use and reduce drug resistant strains effectively.