Detection of mycoplasma and chlamydia from cervical secretions of infertile women and drug sensitivity

OBJECTIVE To explore the relationship between mycoplasma,chlamydia infection and Infertility for Women,guide the clinical treatment.and improre the cure rate of infertility patients.METHODS A total of 356 cases of infertility patients in our hospital were selected from Jan 2009 to Apr 2010,136 cases of primary infertility,220 cases of secondary infertility.Totally 300 cases of normal fertile women were selected as control group.Mycoplasma(Ureaplasma urealyticum Uu,Mycoplasma hominis Mh) and Chlamydia trachomatis(Ct) culture with discharge of the cervix and drug sensitivity test for Uu infection,treat according to drug sensitivity.RESULTS In infertility group,the positive rate of Uu was 55.06%,that of Ct was 4.49%,that of Ct+Uu was 2.25%,In control group,the positive rate of Uu was 24.67%,that of Ct was 1.00%,that of Ct+Uu was 0.33%.The positive rate of UU,CT,CT+UU in Infertility group was significantly different from control group according to the statistics(P0.05),In secondary infertility group,the positive rate of Uu was 59.09%,that of Ct was 5.00%,In primary infertility group,the positive rate of Uu was 48.53%,that of Ct was 3.68%.Uu,Ct infection in secondary infertility was obviously higher than primary infertility group,But the difference was not significant according to the statistics(P0.05),Uu infection was sensitive to pristinamycin,josamycin,doxycycline and tetracycline.CONCLUSION Infection Uu and Ct in reproductive tract is the main factor leading to infertility.Conventional Uu,Ct detection to sterile women,and drug sensitivity test at the same time can help to improve the cure rate of infertility,and control the occurrence of drug resistant strains.