Research on the Coronary Artery Lesion Characteristics and Risk Factors on Patients of Coronary Artery Disease with Type 2 Diabetes Mellitus

Objective: To discuss the clinical features and risk factors of coronary heart disease with type 2 diabetes.Methods: From January 2010 to January 2012,the patients who were diagnosed as coronary heart disease with(DM group: n=227) or without(NDM group: n=229) type 2 diabetes in our hospital by Coronary artery angiography were selected.The blood lipid,blood glucose and results of coronary angiography of the two groups were analyzed retrospectively,the clinical features of Coronary lesions of the two groups were compared,and the effect of blood glucose level on Coronary lesions in coronary heart disease patients with diabetes was investigated.Results: The total cholesterol(TC),triacylglycerol(TG),low density lipoprotein cholesterol(LDL-C) in DM group were significantly higher than those in the NDM group(P0.05),but the high density lipoprotein cholesterol(HDL-C) was significantly lower than that in the NDM group(P0.05);the number of triple vessel disease,diffuse vascular lesion and angiostegnosis of greater than 75% in DM group was more than those in the NDM group(P0.05);the number of diffuse vascular lesion and angiostegnosis of greater than 75% in the group of blood glucose were controlled in a ideal level(group A) were significantly lower than those in the group of blood glucose were controlled in a poor level(group B,P0.05) in coronary heart disease patients with type 2 diabetes.Conclusion: The clinical features of coronary angiography in coronary heart disease patients with type 2 diabetes were characteristic of diffuse and multivessel disease,the degrees of stenosis were severe.Both hyperglycaemia and dyslipidemia were the risk factors of coronary lesions;normalization of blood glucose could improve the severity of coronary lesions and decrease the range of lesions.