Clinical and pathological features of coronary artery disease with type II diabetes

Objective To investigate the risk factors and the pathological features of coronary artery diseases with typeⅡdiabetes.Methods A total of 120 patients with coronary artery disease which were finally diagnosed by coronary artery angiography were recruited.These patients were randomly divided into diabetes group(n=60)and non-diabetes group(n=60).Clinical and angiography characteristics,risk factors and blood fat levels were compared between the two groups.Results In diabetes group,the incidence rate of hypertension was significantly higher than that in non-diabetes group(P0.05).There were no remarkable difference of the incidence rate of smoking,silent myocardial ischemia and myocardial infarction between the two groups(P0.05).The levels of total cholesterol,triglyceride and low density lipoprotein-cholesterol(LDL-C)in the diabetes group were significantly higher than that in the non-diabetes group(P0.05).However,no significant differences in levels of high density lipoprotein cholesterol(HDL-C)were found between the two groups(P0.05).In addition,when in contrast to non-diabetes group,multi-vessel lesion and diffused lesion of coronary artery were more common in diabetes group(P0.05).Conclusion The incidence rate of hypertension and the levels of TC,TG,LDL-C were significantly higher,synchronously with severer coronary lesions in coronary artery disease with typeⅡdiabete patients.