Clinical study on intensive insulin treatment for type 2 diabetes with continuous insulin pump

Objective To investigate the effect of continuous subcutaneous insulin infusion(CSII) for intensive insulin treatment. Methods 76 patients were studied by CSII method.After under controlled of hyperglycemia,under 5 patients were switched to oral hypoglycemic agent and 68 patients were turned to splitting subcutaneous insulin injection(MSII). Results After CSII for 3 to 12 days,an average 6.2±2.0 days,the hyperglycemia could be controlled effectively.The ratio of basal dose to bolus of insulin was in access to 2:3.The ratio of boluses before three meals was 1∶1∶1.The frequency of hypoglycemia in CSII of each case was 0.06 time/d. Conclusions Since CSII mimicks the physiological insulin secretion,hyperglycemia can be controlled more effectively,with less hypoglycemia episode,which provides a safe,effective and convenient new method for intensive insulin treatment.