Serum Homocysteine,High Sensitivity C-reactive Protein and D-dimer Levels in Acute Cerebral Infarction

Objective To evaluate homocysteine in patients with acute cerebral infarction,high-sensitivity C-reactive protein and D-dimer levels and the clinical significance.Methods From June 2008 to June 2010 in our hospital 110 patients with acute cerebral infarction,established as infarction,another healthy choice in our hospital over the same period were 100 cases set to the healthy control group,respectively,a comparative analysis of two different lesions and different levels of Hcy,hs-CRP,DD levels.Which Hcy,hs-CRP with Japanese Toshiba TBA-40 automatic biochemical analyzer.D-dimer were detected by double-antibody sandwich assay.Results ① acute cerebral infarction,110 patients with serum Hcy,hs-CRP,DD levels were significantly higher than the control group,two sets of these indicators,respectively,the difference was statistically significant(P0.05 or P0.01).②Large infarct lesion in patients with Hcy,hs-CRP,DD were significantly higher than the content of small infarction lesions,the difference was statistically significant.③Lesions in patients with severe infarction Hcy,hs-CRP,DD were significantly higher than the mild,moderate levels of infarct lesion,the difference was statistically significant.Conclusion The incidence of acute cerebral infarction,development and Hcy,hs-CRP,D-dimer are closely related,the above indicators will gradually become a routine clinical diagnostic test indicator of acute cerebral infarction,cerebral infarction in patients with above target detection to provide a reliable basis for clinical treatment,which play an important role in prevention.