The clinical significance of homocysteine,high-sensitivity C-reactive protein in patients with acute cerebral infarction

Objective To investigate clinical significance of detection homocysteine(Hcy),high-sensitivity C-reactive protein(hs-CRP) of patients with acute cerebral infarction.Methods Serected 32 cases diagnosed patients with acute cerebral infarction in our hospital from January 2011 to January 2012,30 healthy subjects as control group,deteced the Hcy,hs-CRP changes,and cerebral infarction group Hcy,hs-CRP changes after two weeks of treatment.Results The 32 patients with acute cerebral infarction Hcy was(16.43±3.88) μmol/L,hs-CRP was(4.28±0.27) mg/L and 30 healthy control patients Hcy was(7.32±1.21) μmol/L,Hs-CRP was(1.12±0.34) mg/L,acute cerebral infarction cases of Hcy,hs-CRP content was significantly higher than the healthy control group,the two groups were compared,the difference of Hcy,hs-CRP was statistically significant betwecen two groups(P 0.05);case group admission Hcy(17.34±3.89) μmol/L,hs-CRP was(3.61±0.35) mg/L,after two weeks of treatment the case group Hcy(11.96±4.02) μmol/L,hs-CRP(1.24±0.52)mg/L,the treatment before and after treatment were compared,after treatment 2 weeks,the patient group of Hcy,Hs-CRP content was significantly lower than the time of admission,the difference was statistically significant(P 0.05).Conclusion Homocysteine and high-sensitivity C-reactive protein detection,treatment and monitoring of the disease and the prognosis for the diagnosis of acute cerebral infarction has important clinical diagnostic value.