Combination of “Jianpi Jiedu Decoction”and Capecitabine for the Treatment of Advanced Colorectal Cancer

Objective: To observe the clinical efficacy ofJianpi Jiedu Decoctioncombined with Capecitabine in treating advanced colorectal cancer. Methods: Sixty cases with colorectal cancer were randomly divided into two groups: control group in which 30 cases were treated by Capecitabine Tablet,and treatment group in which 30 cases were treated byJianpi Jiedu Decoctionand Capecitabine Tablet. Twenty days as a course,and treated for 2 weeks. The clinical efficacy,TCM syndrome, quality of life and adverse reaction were observed. Results: No statistical significance was found in clinical efficacy between the two groups ( P 0. 05) ; after treatment,the TCM syndrome score in treatment group was decreased significantly ( P 0. 05) , and the TCM syndrome score in treatment group was lower than that of the controls ( P 0. 05) ; no statistical significance was found in TCM syndrome between the two groups ( P 0. 05) ; the QOL score in both of the groups were decreased markedly after treatment ( P 0. 05 ) ,and the QOL score in treatment group was lower than that of the controls ( P 0. 05 ) ; the occurrence rate of adverse reaction in treatment group was lower than that of the controls ( P 0. 05) . Conclusion: Jianpi Jiedu Decoctionis effective to improve the clinical syndromes,improve the QOL and reduce the adverse reaction in patients with advanced colorectal cancer.