Effect of sufentanil or flurbiprofen axetil combined with tramadol hydrochloride on patients in recovery period after remifentanil-based general anesthesia
Pan Song
Abstract
Pan Song
Abstract
Objective:To explore the effect of sufentail or flurbiprofen axetil combined with tramadol hydrochloride on patients in the recovery period after remifentanil-based general anesthesia.Methods:Forty patients undergoing laparoscopic cholecystectomy were evenly divided into two groups:sufentanil group(group A) and flurbiprofen axetil combined with tramadol hydrochloride group(group B).Group A received intravenous injection of 0.15 μg/kg sufentanil five minutes before the end of the operation,and group B received intravenous injection of 50 mg flurbiprofen axetil ten minutes before the operation and 50 mg flurbiprofen axetil with 2 mg/kg tramadol hydrochloride ten minutes before the end of the operation.The recovery time,verbal rating scale and incidence of side effects were evaluated.Results:The recovery time of group A was longer than that of group B(P0.01).The VRS of group B at 10,20 and 30 min after extubation was significantly higher than that of group A(P0.01).The incidence of side effects was similar 2 h after extubation between the two groups(P0.05).Conclusions:Sufentanil provides more effective analgesia than flurbiprofen axetil combined with tramadol hydrochloride for patients in the early recovery period after remifentanil-based general anesthesia.
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Objective:To explore the effect of sufentail or flurbiprofen axetil combined with tramadol hydrochloride on patients in the recovery period after remifentanil-based general anesthesia.Methods:Forty patients undergoing laparoscopic cholecystectomy were evenly divided into two groups:sufentanil group(group A) and flurbiprofen axetil combined with tramadol hydrochloride group(group B).Group A received intravenous injection of 0.15 μg/kg sufentanil five minutes before the end of the operation,and group B received intravenous injection of 50 mg flurbiprofen axetil ten minutes before the operation and 50 mg flurbiprofen axetil with 2 mg/kg tramadol hydrochloride ten minutes before the end of the operation.The recovery time,verbal rating scale and incidence of side effects were evaluated.Results:The recovery time of group A was longer than that of group B(P0.01).The VRS of group B at 10,20 and 30 min after extubation was significantly higher than that of group A(P0.01).The incidence of side effects was similar 2 h after extubation between the two groups(P0.05).Conclusions:Sufentanil provides more effective analgesia than flurbiprofen axetil combined with tramadol hydrochloride for patients in the early recovery period after remifentanil-based general anesthesia.
Key concepts: Medicine, Tramadol Hydrochloride, Tramadol, Anesthesia, Sufentanil, Remifentanil, Flurbiprofen, Analgesic