Clinical Observation of Flurbiprofen Axetil or Tramadol Combined with Sufentanil on Analgesic of Colon Carcinoma after Radical Operation

Objective To compare the analgesic effect and complications of flurbiprofen axetil or tramadol combined with sufentanil on analgesic of colon carcinoma after radical operation. Methods 72 patients with ASA Ⅰ ~ Ⅱ level laparoscopic radical operation for colon carcinoma were randomly divided into flurbiprofen axetil + sufentanil group group( group A) and tramadol + sufentanil group( group B),each with 36 cases. Awakening and extubation time( T1) and orientation recovery time( T2) after operation,automatic pressing times during PCIA,analgesia score and sedation score 4 h,12 h,24 h and 48 h after operation and occurrence of adverse reaction after operation of the 2 groups were compared. Results There were no significant differences between the 2 groups in awakening and extubation time( T1) and orientation recovery time( T2),automatic pressing times during PCIA,analgesia score and sedation score 4 h,12 h,24 h and 48 h after operation( all P 0. 05). Occurrence rate of adverse reaction of group A and group B were 16. 7%( 6 cases) and 55. 6%( 20 cases)( P 0. 05). Conclusion Flurbiprofen axetil combined with sufentanil has the equal analgesic effect with tramadol combined with sufentanil,but has lower occurrence rate of adverse reaction.