Therapeutic effect of combination and sequencial interventional treatment on primary liver cancer with transcatheter arterial chemoembolization combined with radioactive colloidal phosephate and percutaneous ethanol injection under ultrasound

Objective To evaluate the clinical efficacy of transcatheter arterial chemoembolization (TACE) combined with radioactive colloidel phosephate ( 32 P) and percutaneous ethanol injection (PEI) in the treatment of primary liver cancer (PLC). Methods 51 cases of moderate and advanced stages of PLC were divided into two groups, 23 cases were treated with TACE and followed subsequently by 32 P and PEI (group A). 28 cases were treated with TACE alone (group B). Results The rates of reduction in tumor diameter and tumor complete necrosis and the decline in serum AFP level in group A were 91.29%, 80.00% and 87.5%, while those of group B were 39.27%, 30.43% and 41.46% respectively. There was significant difference between the two groups ( P 0.01). The 6 month, 1-,2-,3-year survival rates of group A were 95.65%, 86.95%, 56.52%, 20.73%, respectively; in contrast, those of group B were 64.28%, 39.28%, 17.85%, 00.00%,respectively ( P 0.01). Conclusions The combination and sequencial interventional treatment on PLC with TACE combined with 32 P and PEI is an efficient method for increasing the survival rate.