2002Acta Scientiarum Naturalium Universitatis SunyatseniRequires access

Therapeutic Effect of Transcatheter Arterial Chemoembolization Combined with Percutaneous Ethanol Injection in Hepatocellular Carcinoma

QUZengqiang, QIANGuojun, CHENHan

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Abstract

Objective:To evaluate the clinical efficacy of the combined treatment with transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) on hepatocellular carcinoma (HCC). Methods:312 patients with moderate or advanced HCCs were divided into two groups: 170 cases underwent TACE treatment alone, 142 cases were treated with TACE and PEI under B-ultrasotmd guidance. Results:The rates of reduction in tumor diameter and the decline in serum AFP level were 41.2% and 40.4% in the TACE group and 75.4% and 74.1% in the TACE + PEI group respectively. The 6, 12 and 24 months survival rates in the TACE group were 77.1%,34.1% and 18.8%,respectively and in the TACE + PEI group 87.3%, 62.0% and 38.0%, respectively. Overall, there was a significant difference between the two treatment groups (P<0.05). Conclusion:Treatment on HCCs with TACE + PEI is convenient, safe and results in better survival rates than TACE alone.

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Objective:To evaluate the clinical efficacy of the combined treatment with transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) on hepatocellular carcinoma (HCC). Methods:312 patients with moderate or advanced HCCs were divided into two groups: 170 cases underwent TACE treatment alone, 142 cases were treated with TACE and PEI under B-ultrasotmd guidance. Results:The rates of reduction in tumor diameter and the decline in serum AFP level were 41.2% and 40.4% in the TACE group and 75.4% and 74.1% in the TACE + PEI group respectively. The 6, 12 and 24 months survival rates in the TACE group were 77.1%,34.1% and 18.8%,respectively and in the TACE + PEI group 87.3%, 62.0% and 38.0%, respectively. Overall, there was a significant difference between the two treatment groups (P<0.05). Conclusion:Treatment on HCCs with TACE + PEI is convenient, safe and results in better survival rates than TACE alone.

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Available abstract

Objective:To evaluate the clinical efficacy of the combined treatment with transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) on hepatocellular carcinoma (HCC). Methods:312 patients with moderate or advanced HCCs were divided into two groups: 170 cases underwent TACE treatment alone, 142 cases were treated with TACE and PEI under B-ultrasotmd guidance. Results:The rates of reduction in tumor diameter and the decline in serum AFP level were 41.2% and 40.4% in the TACE group and 75.4% and 74.1% in the TACE + PEI group respectively. The 6, 12 and 24 months survival rates in the TACE group were 77.1%,34.1% and 18.8%,respectively and in the TACE + PEI group 87.3%, 62.0% and 38.0%, respectively. Overall, there was a significant difference between the two treatment groups (P<0.05). Conclusion:Treatment on HCCs with TACE + PEI is convenient, safe and results in better survival rates than TACE alone.

Key concepts: Percutaneous ethanol injection, Transcatheter arterial chemoembolization, Hepatocellular carcinoma, Medicine, Percutaneous, Gastroenterology, Therapeutic effect, Internal medicine

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