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2004•Zhejiang Medical JournalRequires access

The role of plasma BNP in risk stratification and prognosis of patients with congestive heart failure

Yin Liu

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Abstract

Objective To evaluate the role of plasma B-type natriuretic peptide(BNP) in the risk stratification and the prognosis of patients with congestive heart failure(CHF). Methods The levels of plasma BNP were measured in 66 CHF patients (CHF group) and 22 patients without CHF (control group). Two groups were compared with the rate of readmission for worsening CHF in 30 days and the mortality due to heart failure among BNP100pg/ml group(33 cases), 100≤BNP400pg/ml group(30 cases) and BNP≥400pg/ml group(25 cases), and the relationship of BNP with LVEF, UA and CK-MB were evaluated. Results The plasma BNP levels in CHF group were higher than those in control group. The plasma BNP levels were significantly associated with the rate of readmission in 30 days and the mortality (P0.01). Conclusion BNP levels can be used as a indicator for risk stratification and prognosis of patients with congestive heart failure.

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Objective To evaluate the role of plasma B-type natriuretic peptide(BNP) in the risk stratification and the prognosis of patients with congestive heart failure(CHF). Methods The levels of plasma BNP were measured in 66 CHF patients (CHF group) and 22 patients without CHF (control group). Two groups were compared with the rate of readmission for worsening CHF in 30 days and the mortality due to heart failure among BNP100pg/ml group(33 cases), 100≤BNP400pg/ml group(30 cases) and BNP≥400pg/ml group(25 cases), and the relationship of BNP with LVEF, UA and CK-MB were evaluated. Results The plasma BNP levels in CHF group were higher than those in control group. The plasma BNP levels were significantly associated with the rate of readmission in 30 days and the mortality (P0.01). Conclusion BNP levels can be used as a indicator for risk stratification and prognosis of patients with congestive heart failure.

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Available abstract

Objective To evaluate the role of plasma B-type natriuretic peptide(BNP) in the risk stratification and the prognosis of patients with congestive heart failure(CHF). Methods The levels of plasma BNP were measured in 66 CHF patients (CHF group) and 22 patients without CHF (control group). Two groups were compared with the rate of readmission for worsening CHF in 30 days and the mortality due to heart failure among BNP100pg/ml group(33 cases), 100≤BNP400pg/ml group(30 cases) and BNP≥400pg/ml group(25 cases), and the relationship of BNP with LVEF, UA and CK-MB were evaluated. Results The plasma BNP levels in CHF group were higher than those in control group. The plasma BNP levels were significantly associated with the rate of readmission in 30 days and the mortality (P0.01). Conclusion BNP levels can be used as a indicator for risk stratification and prognosis of patients with congestive heart failure.

Key concepts: Medicine, Heart failure, Internal medicine, Cardiology, Risk stratification, Natriuretic peptide, Ejection fraction, Brain natriuretic peptide

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