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2008•The Journal of Clinical PsychiatryRequires access

Comperison of quetiapine and aripiprazole in the treatment of first episode schizophrenia

AN Bao-f

Open publisher page 2 citations

Abstract

Objective:To compare the efficacy and safety of quetiapine and aripiprazole in the treatment of first episode schizophrenia. Method:70 cases of patients with schizophrenia were divided into two groups treated with quetiapine or aripiprazole respectively for 8 weeks.The positive and negative symptom scale(PANSS) and treatment emergent symptoms effect scale(TESS) were used to evaluate the efficacy and adverse effect,respectively. Results:The efficacy rates of quetiapine group was 85.7% after 8 weeks while that was 82.9% in aripiprazole group.There was no significant difference between the two groups of efficacy rates(P0.05). Conclusion:Quetiapine is effective and safe as aripiprazole for the treatment of first episode schizophrenia and fewer side effects.

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What this paper is about

Objective:To compare the efficacy and safety of quetiapine and aripiprazole in the treatment of first episode schizophrenia. Method:70 cases of patients with schizophrenia were divided into two groups treated with quetiapine or aripiprazole respectively for 8 weeks.The positive and negative symptom scale(PANSS) and treatment emergent symptoms effect scale(TESS) were used to evaluate the efficacy and adverse effect,respectively. Results:The efficacy rates of quetiapine group was 85.7% after 8 weeks while that was 82.9% in aripiprazole group.There was no significant difference between the two groups of efficacy rates(P0.05). Conclusion:Quetiapine is effective and safe as aripiprazole for the treatment of first episode schizophrenia and fewer side effects.

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Available abstract

Objective:To compare the efficacy and safety of quetiapine and aripiprazole in the treatment of first episode schizophrenia. Method:70 cases of patients with schizophrenia were divided into two groups treated with quetiapine or aripiprazole respectively for 8 weeks.The positive and negative symptom scale(PANSS) and treatment emergent symptoms effect scale(TESS) were used to evaluate the efficacy and adverse effect,respectively. Results:The efficacy rates of quetiapine group was 85.7% after 8 weeks while that was 82.9% in aripiprazole group.There was no significant difference between the two groups of efficacy rates(P0.05). Conclusion:Quetiapine is effective and safe as aripiprazole for the treatment of first episode schizophrenia and fewer side effects.

Key concepts: Aripiprazole, Quetiapine, Schizophrenia (object-oriented programming), Negative symptom, Positive and Negative Syndrome Scale, Psychology, Medicine, Psychiatry

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Comperison of quetiapine and aripiprazole in the treatment of first episode schizophrenia — Research Paper | ScholarLens