Comparative study of aripiprazole and quetiapine in the treatment of male schizophrenia patients

Objective To compare the effects of aripiprazole and quetiapine in the treatment of male schizophrenia patients on the efficacy. Methods One hundred male schizophrenia patients were randomly divided into the aripiprazole group (n=50) and quetiapine group (n=50), which were treaded with aripiprazole or quetiapine for 8 weeks, respectively. The clinical efficacy was evaluated by PANSS and the adverse reactions were evaluated by RSESE. Results At the end of the eighth week, the effective rates of the aripiprazole group and the quetiapine group were 94.00% and 92.00% , respectively, with no statistically significant difference between the two groups. The incidence of adverse reactions in the aripiprazole group was significantly lower than that in the quetiapine group. Conclusion Aripiprazole is as effective as quetiapine in the treatment of male schizophrenia patients, and aripiprazole results in fewer adverse effects.