2009•Hainan yixueRequires access

Clinical effects of non-invasive positive pressure ventilation on acute exacerbation of chronic obstructive pulmonary disease accompanied with respiratory failure

Yang Jin-wan

Abstract

Objective To evaluate the value of non-invasive positive pressure ventilation(NIPPV)in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)accompanied with respiratory failure.Methods 64 patients with AECOPD were randomly divided into ventilation group(n=32)and control group(n=32),which received conventional medical therapy plus NIPPV and conventional medical therapy only,respectively.The blood gas analysis,breath rate,heart rate and consciousness-clear rate of patients before and after the treatment were compared between the two groups.Results The blood gas analysis,breath rate,heart rate and consciousness-clear rate improved more significantly in the ventilation group than those in the control group.(P0.05).Conclusion NIPPV has positive effect on AECOPD accompanied with respiratory failure.

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Key concepts: Medicine, Acute exacerbation of chronic obstructive pulmonary disease, Positive pressure ventilation, Exacerbation, Ventilation (architecture), Respiratory failure, Arterial blood, Pulmonary disease