2008•Journal of Clinical Pulmonary MedicineRequires access
Clinic effect of non-invasive positive pressure ventilation in treatment for patients with a cute exacerbation of chronic obstructive pulmonary disease and respiratory failure
Zeng Hongyu
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Abstract
Objective To evaluate the value of non-invasive positive pressure ventilation(NIPPV)in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)with respiratory failure.Methods 81 patients with AECOPD were randomly divided into trial group(42 cases)and control group(39 cases),which respectively received conventional medical therapy plus NIPPV and conventional medical therapy only.The of blood gas analysis,breath rate,heart rate and tracheal cannula rate of patients before and after the treatment were compared between the two groups.Results The blood gas analysis,heart rate,and breath rate improved more significantly in the trial group than those in the control groups.meanwhile,the tracheal cannula rate in the trial groups is much lower than the control group(P0.05).Conclusion Non-invasive positive pressure ventilation has positive effects on patients of AECOPD with respiratory failure significantly.